Publications
Fischer, M.D., Graham, P, and Pick, L. (2024) The ftz upstream element drives late ftz stripes but is not required for regulation of Ftz target genes. Devleopmental Biology 505:141-147. doi: 10.1016/j.ydbio.2023.11.004
Wexler, J., Pick, L. and Chipman, A. (2023) Segmental expression of two ecdysone pathway genes during embryogenesis of hemimetabolous insects. Developmental Biology 498:87-96. doi: 10.1016/j.ydbio.2023.03.008
Reding, K. , Le, M. and Pick, L. (2023) Genome editing of the vermilion locus generates a visible eye color marker for Oncopeltus fasciatus. Scientific Reports 13, 4188 doi: 10.1038/s41598-023-31145-2
Cheatle Jarvela, A.M., Trelstad, C. S. and Pick, L. (2023) Anterior-posterior patterning of segments in Anopheles stephensi offers insights into the transition from sequential to simultaneous segmentation in holometabolous insects. J. Exp. Zool – B
https://doi.org/10.1002/jez.b.23102
Graham, P. L., Fischer, M., Giri, A. and Pick, L. (2021) The fushi tarazu zebra element is not required for Drosophila viability or fertility. G3: Genes, Genomes, Genetics 11(11): https://doi.org/10.1093/g3journal/jkab300
Cheatle Jarvela, A.M., Trelstad, C. S. and Pick, L. (2020) Regulatory gene function handoff allows essential gene loss in mosquitoes. Communications Biology 3, 540 https://doi.org/10.1038/s42003-020-01203-w
Reding, K. and Pick, L. (2020) High Efficiency CRISPR/Cas9 mutagenesis of the white gene in the milkweed bug Oncopeltus fasciatus. Genetics: 215, 1027- 1037; https://doi.org/10.1534/genetics.120.303269 PMID: 32493719 https://www.genetics.org/content/215/4/1027
Hernandez, J., Pick, L. & Reding, K. (2020) Oncopeltus-like gene expression patterns in Murgantia histrionica, a new hemipteran model system, suggest ancient regulatory network divergence. EvoDevo 11, 9 . https://doi.org/10.1186/s13227-020-00154-x [Link]
Reding, K., Chen, M., Lu, Y., Cheatle Jarvela, A.M., & Pick, L. (2019) Shifting roles of Drosophila pair-rule gene orthologs: segmental expression and function in the milkweed bug Oncopeltus fasciatus. Development. 146: dev181453 doi: 10.1242/dev.181453 [Link]
Panfilio, K.A., Vargas Jentzsch, I.M., Benoit, J.B., Erezyilmaz, D., Suzuki, Y., Colella, S., Robertson, H.M., Poelchau, M.F., Waterhouse, R.M., Ioannidis, P., Weirauch, M.T., Hughes, D.S.T., Murali, S.C., Werren, J.H., Jacobs , C.G.C., Duncan, E.J., Armisén, D., Vreede, B.M.I., Baa-Puyoulet, P., Berger, C.S., Chang, C-C., Chao, H., Chen, C-J.M., Chen, Y-T., Childers, C.P., Chipman, A.D., Cridge, A.G., Crumière, A.J.J., Dearden, P.K., Didion, E.M., Huyen Dinh, H., Doddapaneni, H., Dolan, A., Dugan, S., Extavour, C.G., Febvay, G., Friedrich, M., Ginzburg, N., Han, Y., Heger, P., Horn, T., Hsiao, Y.-M., Jennings, E.C., Johnston, J.S., Jones, T.E., Jones, J.W., Khila, A., Koelzer, S., Kovacova, V., Leask, M., Lee, S.L., Lee, C.-L., Lovegrove, M.R., Lu, H.-L., Lu, Y., Moore, P.J., Munoz-Torres, M.C., Muzny, D.M., Palli, S.R., Parisot, N., Pick, L., Porter, M., Qu, J., Refki, P.N., Richter, R., Rivera Pomar, R., Rosendale, A.J., Roth, S., Sachs, L., Santos, M.E., Seibert, J., Sghaier, E., Shukla, J.N., Stancliffe, R.J., Tidswell, O., Traverso, L., van der Zee, M., Viala, S., Worley, K.C., Zdobnov, E.M., Gibbs, R.G., Richards, S. (2019) Molecular evolutionary trends and feeding ecology diversification in the Hemiptera, anchored by the milkweed bug genome. Genome Biology, 2:64. doi: 10.1186/s13059-019-1660-0. PMID:30935422.
Graham, P. L., Anderson, W. R., Brandt, E. A., Xiang, J. & Pick, L. (2019) Dynamic expression of Drosophila segmental cell surface-encoding genes and their pair-rule regulators. Developmental Biology. doi:10.1016/j.ydbio.2019.01.015 [Link]
Splinter, K., Adams D.R., Bacino, C.A., Bellen, H.J., Bernstein, J.A., Cheatle-Jarvela, A.M., Eng, C.M., Esteves, C., Gahl, W.A., Hamid, R., Jacob, H.J., Kikani, B., Koeller, D.M., Kohane, I.S., Lee, B.H., Loscalzo, J., Luo, X., McCray, A.T., Metz, A.T., Mulvihill, J.J., Nelson, S.F., Palmer, C.G.S., Phillips, J.A. 3rd, Pick, L., Postlethwait, J.H., Reuter, C., Shashi, V., Sweetser, D.A., Tifft, C.J., Walley, N.M., Wangler, M.F., Westerfield, M., Wheeler, M.T., Wise, A.L., Worthey, E.A., Yamamoto, S., Ashley, E.A., Undiagnosed Diseases Network. (2018) Effect of Genetic Diagnosis on Patients with Previously Undiagnosed Disease. New England Journal of Medicine, 2018 Oct 10. doi: 10.1056/NEJMoa1714458. [Link]
Daffern, N., Chen, Z., Zhang, Y., Pick, L., and Radhakrishnan,I. (2018) Solution NMR Studies of the Ligand-Binding Domain of an Orphan Nuclear Receptor Reveals a Dynamic Helix in the Ligand-Binding Pocket. Biochemistry 57:1977-1986. doi: 10.1021/acs.biochem.8b00069. PMID:29547262 [Pubmed link]
Xiang, J., Reding, K., Heffer, A. and Pick, L. (2017) Conservation and variation of pair-rule patterning mechanisms revealed in Dermestes maculatus. Development, 144:4625-4636. doi: 10.1242/dev.154039. [Pubmed link]
Lu, Y., Chen, M., Reding, K., & Pick, L. (2017) Establishment of molecular genetic approaches to study gene expression and function in an invasive hemipteran, Halyomorpha halys. EvoDevo, 8(15). [Pubmed link]
Cheatle Jarvela, A.M. and Pick, L. (2017) “The Function and Evolution of Nuclear Receptors in Insect Embryonic Development” In Current Topics in Developmental Biology, 125:39-70. doi: 10.1016/bs.ctdb.2017.01.003. [Pubmed link]
Graham, P. and Pick, L. (2017) “Drosophila as a Model for Diabetes and Diseases of Insulin Resistance.” In Current Topics in Developmental Biology, 121:397-419. doi: 10.1016/bs.ctdb.2016.07.011. [Pubmed link]
Book Editor, Pick L., (2017) Fly Models of Human Diseases in Current Topics in Developmental Biology, 121:xv-xix. doi: 10.1016/S0070-2153(16)30214-9. PMID:28057310
Field, A., Xiang, J., Anderson W.R., and Pick, L. (2016) Activation of Ftz-F1- responsive genes through Ftz/Ftz-F1 dependent enhancers. PLoS One, 11(10):e0163128. doi: 10.1371/journal.pone.0163128 [Pubmed link]
Extavour, C.G. and Pick, L. (2016) Editorial Overview: Development, regulation and evolution of organ systems. Current Opinion in Insect Science 13: vii-ix. [Pubmed link]
Xiang, J., Reding, K. and Pick, L. (2016) Rearing and double-stranded RNA- mediated gene knockdown in the hide beetle, Dermestes maculatus. doi: 10.3791/54976. PMID:28060304. JoVE.
Graham, P., & Pick, L. (2016). Drosophila as a Model for Diabetes and Diseases of Insulin Resistance. In Current Topics in Developmental Biology. [Pubmed link]
Cheatle Jarvela, A.M., and Pick, L. (2016). Evo-Devo: Discovery of Diverse Mechanisms Regulating Development. Curr Top Dev Biol. [Pubmed link]
Xiang, J., Forrest, I.S., and Pick, L. (2015) Dermestes maculatus: an intermediate-germ beetle model system for evo-devo, EvoDevo. [Pubmed link]
Pick, L. (2015) Hox genes, evo-devo and the case of the ftz gene. Chromosoma. [Pubmed link]
Ioannidis, P., Lu, Y., Kumar, N., Creasy, T., Daugherty, S., Chibucos, M.C., Orvis, J., Shetty, A., Ott, S., Flowers, M., Sengamalay, N., Tallon, L. J., Pick, L., Dunning Hotopp, J.C. (2014). Rapid transciptome sequencing of an invasive pest, the brown marmorated stink bug Halyomorpha halys, BMC Genomics. [PubMed link]
Li, CR., Guo, D. and Pick, L. (2014) Independent signaling by Drosophila insulin receptor for axon guidance and growth. Front Physiol 4:385 [Pubmed Link]
Heffer, A., Grubbs, N., Mahaffey, J. and Pick, L. (2013) The evolving role of the orphan nuclear receptor ftz-f1, a pair-rule segmentation gene. Evol Dev 15:406-17 [Pubmed Link]
Crivat, G., Lizunov, V.A., Li, C. R., Stenkula, K.G., Zimmerberg, J., Cushmam, S.W.,and Pick, L. (2013) Insulin stimulates translocation of human GLUT4 to the membrane in fat bodies of transgenic Drosophila melanogaster. PLoS One 10.1371 [Link]
Wexler, J., Pick, L. and Chipman, A. (2023) Segmental expression of two ecdysone pathway genes during embryogenesis of hemimetabolous insects. Developmental Biology 498:87-96. doi: 10.1016/j.ydbio.2023.03.008
Reding, K. , Le, M. and Pick, L. (2023) Genome editing of the vermilion locus generates a visible eye color marker for Oncopeltus fasciatus. Scientific Reports 13, 4188 doi: 10.1038/s41598-023-31145-2
Cheatle Jarvela, A.M., Trelstad, C. S. and Pick, L. (2023) Anterior-posterior patterning of segments in Anopheles stephensi offers insights into the transition from sequential to simultaneous segmentation in holometabolous insects. J. Exp. Zool – B
https://doi.org/10.1002/jez.b.23102
Graham, P. L., Fischer, M., Giri, A. and Pick, L. (2021) The fushi tarazu zebra element is not required for Drosophila viability or fertility. G3: Genes, Genomes, Genetics 11(11): https://doi.org/10.1093/g3journal/jkab300
Cheatle Jarvela, A.M., Trelstad, C. S. and Pick, L. (2020) Regulatory gene function handoff allows essential gene loss in mosquitoes. Communications Biology 3, 540 https://doi.org/10.1038/s42003-020-01203-w
Reding, K. and Pick, L. (2020) High Efficiency CRISPR/Cas9 mutagenesis of the white gene in the milkweed bug Oncopeltus fasciatus. Genetics: 215, 1027- 1037; https://doi.org/10.1534/genetics.120.303269 PMID: 32493719 https://www.genetics.org/content/215/4/1027
Hernandez, J., Pick, L. & Reding, K. (2020) Oncopeltus-like gene expression patterns in Murgantia histrionica, a new hemipteran model system, suggest ancient regulatory network divergence. EvoDevo 11, 9 . https://doi.org/10.1186/s13227-020-00154-x [Link]
Reding, K., Chen, M., Lu, Y., Cheatle Jarvela, A.M., & Pick, L. (2019) Shifting roles of Drosophila pair-rule gene orthologs: segmental expression and function in the milkweed bug Oncopeltus fasciatus. Development. 146: dev181453 doi: 10.1242/dev.181453 [Link]
Panfilio, K.A., Vargas Jentzsch, I.M., Benoit, J.B., Erezyilmaz, D., Suzuki, Y., Colella, S., Robertson, H.M., Poelchau, M.F., Waterhouse, R.M., Ioannidis, P., Weirauch, M.T., Hughes, D.S.T., Murali, S.C., Werren, J.H., Jacobs , C.G.C., Duncan, E.J., Armisén, D., Vreede, B.M.I., Baa-Puyoulet, P., Berger, C.S., Chang, C-C., Chao, H., Chen, C-J.M., Chen, Y-T., Childers, C.P., Chipman, A.D., Cridge, A.G., Crumière, A.J.J., Dearden, P.K., Didion, E.M., Huyen Dinh, H., Doddapaneni, H., Dolan, A., Dugan, S., Extavour, C.G., Febvay, G., Friedrich, M., Ginzburg, N., Han, Y., Heger, P., Horn, T., Hsiao, Y.-M., Jennings, E.C., Johnston, J.S., Jones, T.E., Jones, J.W., Khila, A., Koelzer, S., Kovacova, V., Leask, M., Lee, S.L., Lee, C.-L., Lovegrove, M.R., Lu, H.-L., Lu, Y., Moore, P.J., Munoz-Torres, M.C., Muzny, D.M., Palli, S.R., Parisot, N., Pick, L., Porter, M., Qu, J., Refki, P.N., Richter, R., Rivera Pomar, R., Rosendale, A.J., Roth, S., Sachs, L., Santos, M.E., Seibert, J., Sghaier, E., Shukla, J.N., Stancliffe, R.J., Tidswell, O., Traverso, L., van der Zee, M., Viala, S., Worley, K.C., Zdobnov, E.M., Gibbs, R.G., Richards, S. (2019) Molecular evolutionary trends and feeding ecology diversification in the Hemiptera, anchored by the milkweed bug genome. Genome Biology, 2:64. doi: 10.1186/s13059-019-1660-0. PMID:30935422.
Graham, P. L., Anderson, W. R., Brandt, E. A., Xiang, J. & Pick, L. (2019) Dynamic expression of Drosophila segmental cell surface-encoding genes and their pair-rule regulators. Developmental Biology. doi:10.1016/j.ydbio.2019.01.015 [Link]
Splinter, K., Adams D.R., Bacino, C.A., Bellen, H.J., Bernstein, J.A., Cheatle-Jarvela, A.M., Eng, C.M., Esteves, C., Gahl, W.A., Hamid, R., Jacob, H.J., Kikani, B., Koeller, D.M., Kohane, I.S., Lee, B.H., Loscalzo, J., Luo, X., McCray, A.T., Metz, A.T., Mulvihill, J.J., Nelson, S.F., Palmer, C.G.S., Phillips, J.A. 3rd, Pick, L., Postlethwait, J.H., Reuter, C., Shashi, V., Sweetser, D.A., Tifft, C.J., Walley, N.M., Wangler, M.F., Westerfield, M., Wheeler, M.T., Wise, A.L., Worthey, E.A., Yamamoto, S., Ashley, E.A., Undiagnosed Diseases Network. (2018) Effect of Genetic Diagnosis on Patients with Previously Undiagnosed Disease. New England Journal of Medicine, 2018 Oct 10. doi: 10.1056/NEJMoa1714458. [Link]
Daffern, N., Chen, Z., Zhang, Y., Pick, L., and Radhakrishnan,I. (2018) Solution NMR Studies of the Ligand-Binding Domain of an Orphan Nuclear Receptor Reveals a Dynamic Helix in the Ligand-Binding Pocket. Biochemistry 57:1977-1986. doi: 10.1021/acs.biochem.8b00069. PMID:29547262 [Pubmed link]
Xiang, J., Reding, K., Heffer, A. and Pick, L. (2017) Conservation and variation of pair-rule patterning mechanisms revealed in Dermestes maculatus. Development, 144:4625-4636. doi: 10.1242/dev.154039. [Pubmed link]
Lu, Y., Chen, M., Reding, K., & Pick, L. (2017) Establishment of molecular genetic approaches to study gene expression and function in an invasive hemipteran, Halyomorpha halys. EvoDevo, 8(15). [Pubmed link]
Cheatle Jarvela, A.M. and Pick, L. (2017) “The Function and Evolution of Nuclear Receptors in Insect Embryonic Development” In Current Topics in Developmental Biology, 125:39-70. doi: 10.1016/bs.ctdb.2017.01.003. [Pubmed link]
Graham, P. and Pick, L. (2017) “Drosophila as a Model for Diabetes and Diseases of Insulin Resistance.” In Current Topics in Developmental Biology, 121:397-419. doi: 10.1016/bs.ctdb.2016.07.011. [Pubmed link]
Book Editor, Pick L., (2017) Fly Models of Human Diseases in Current Topics in Developmental Biology, 121:xv-xix. doi: 10.1016/S0070-2153(16)30214-9. PMID:28057310
Field, A., Xiang, J., Anderson W.R., and Pick, L. (2016) Activation of Ftz-F1- responsive genes through Ftz/Ftz-F1 dependent enhancers. PLoS One, 11(10):e0163128. doi: 10.1371/journal.pone.0163128 [Pubmed link]
Extavour, C.G. and Pick, L. (2016) Editorial Overview: Development, regulation and evolution of organ systems. Current Opinion in Insect Science 13: vii-ix. [Pubmed link]
Xiang, J., Reding, K. and Pick, L. (2016) Rearing and double-stranded RNA- mediated gene knockdown in the hide beetle, Dermestes maculatus. doi: 10.3791/54976. PMID:28060304. JoVE.
Graham, P., & Pick, L. (2016). Drosophila as a Model for Diabetes and Diseases of Insulin Resistance. In Current Topics in Developmental Biology. [Pubmed link]
Cheatle Jarvela, A.M., and Pick, L. (2016). Evo-Devo: Discovery of Diverse Mechanisms Regulating Development. Curr Top Dev Biol. [Pubmed link]
Xiang, J., Forrest, I.S., and Pick, L. (2015) Dermestes maculatus: an intermediate-germ beetle model system for evo-devo, EvoDevo. [Pubmed link]
Pick, L. (2015) Hox genes, evo-devo and the case of the ftz gene. Chromosoma. [Pubmed link]
Ioannidis, P., Lu, Y., Kumar, N., Creasy, T., Daugherty, S., Chibucos, M.C., Orvis, J., Shetty, A., Ott, S., Flowers, M., Sengamalay, N., Tallon, L. J., Pick, L., Dunning Hotopp, J.C. (2014). Rapid transciptome sequencing of an invasive pest, the brown marmorated stink bug Halyomorpha halys, BMC Genomics. [PubMed link]
Li, CR., Guo, D. and Pick, L. (2014) Independent signaling by Drosophila insulin receptor for axon guidance and growth. Front Physiol 4:385 [Pubmed Link]
Heffer, A., Grubbs, N., Mahaffey, J. and Pick, L. (2013) The evolving role of the orphan nuclear receptor ftz-f1, a pair-rule segmentation gene. Evol Dev 15:406-17 [Pubmed Link]
Crivat, G., Lizunov, V.A., Li, C. R., Stenkula, K.G., Zimmerberg, J., Cushmam, S.W.,and Pick, L. (2013) Insulin stimulates translocation of human GLUT4 to the membrane in fat bodies of transgenic Drosophila melanogaster. PLoS One 10.1371 [Link]
Heffer, A., Xiang, J. and Pick, L. (2013) Variation and constraint in Hox gene evolution. Proc. Natl. Acad. Sci. [Pubmed Link]
Lu, Y., Anderson, W.R., Zhang, H., Feng, S., and Pick, L. (2013) Functional conservation of Drosophila FTZ-F1 and its mammalian homologs suggests ligand-independent regulation of NR5A family transcriptional activity. Development, Genes and Evolution [Pubmed Link]
Lu, Y., Anderson, W.R., Zhang, H., Feng, S., and Pick, L. (2013) Functional conservation of Drosophila FTZ-F1 and its mammalian homologs suggests ligand-independent regulation of NR5A family transcriptional activity. Development, Genes and Evolution [Pubmed Link]
Link]
Pick, L. and Heffer, A. (2012) Hox gene evolution: multiple mechanisms contributing to evolutionary novelties. Annals N.Y. Acad. Sci. [Pubmed Link]
Heffer, A., Löhr, U. and Pick, L. (2011) ftz evolution: findings, hypotheses and speculations (response to DOI 10.1002/bies.201100019). Bioessays 33:910-8. doi: 10.1002/bies.201100112 (Back cover photo) [Pubmed Link]
Heffer, A. and Pick, L. (2011) Rapid isolation of gene homologs across taxa: Efficient identification and isolation of gene orthologs from non-model organism genomes, a technical report. Evo devo. 2:7. [Pubmed Link]
Heffer, A. and Pick, L. (2013) “Conservation and variation in Hox genes: how insect models pioneered the evo-devo field.” Annual Reviews of Entomology 58:161–79 [Pick, L. and Heffer, A. (2012) Hox gene evolution: multiple mechanisms contributing to evolutionary novelties. Annals N.Y. Acad. Sci. [Pubmed Link]
Heffer, A., Löhr, U. and Pick, L. (2011) ftz evolution: findings, hypotheses and speculations (response to DOI 10.1002/bies.201100019). Bioessays 33:910-8. doi: 10.1002/bies.201100112 (Back cover photo) [Pubmed Link]
Heffer, A. and Pick, L. (2011) Rapid isolation of gene homologs across taxa: Efficient identification and isolation of gene orthologs from non-model organism genomes, a technical report. Evo devo. 2:7. [Pubmed Link]
Heffer, A., Shultz, J. and Pick, L. (2010) Surprising flexibility in a conserved transcription factor over 550 million years of evolution. Proc. Natl. Acad. Sci. 107: 18040-18045 [Pubmed Link]
Junell, A., Uvell, H., Davis, M.M., Edlundh-Rose, E., Antonsson, A., Pick, L., Engström, Y. (2010) The POU transcription factor Drifter/Ventral veinless regulates expression of Drosophila immune defense genes. Molecular & Cellular Biology 14:3672-84. [Pubmed Link]
Zhang, H., Liu, J., Li, C.R., Momen, B., Kohanski, R.A. and Pick, L. (2009) Deletion of Drosophila Insulin-Like peptides causes growth defects and metabolic abnormalities. Proc. Natl. Acad. Sci. USA. 106:19617-19622 [Pubmed Link]
Hou, H.Y., Heffer, A., Anderson, W.R., Liu, J., Bowler, T. and Pick, L. (2009) Stripy Ftz target genes are coordinately regulated by Ftz-F1. Developmental Biology 335:442-53. (Cover Photo) [Pubmed Link]
Junell, A., Uvell, H., Pick, L. and Engström, Y. (2007) Isolation of regulators of Drosophila immune defense genes by a double interaction screen in yeast. Insect Biochemistry & Molecular Biology 37: 202-212 [Pubmed Link]
Pick, L. Shultz, J., Anderson, W.R. and Woodard, C. (2006) The Ftz-F1 family: orphan nuclear receptors regulated by novel protein-protein interactions.In "Nuclear Receptors in Development." R. Taneja, Volume editor.Bowler, T.,Kosman, D., Anderson, W.R. and Pick, L. (2006) A computational screen to identify genomic targets of the Ftz/Ftz-F1 homeodomain/nuclear receptor heterodimer. Developmental Biology 299:78-90. [Pubmed Link]
Oishi,K., Gaengel,K., Kamiya,K., Kim, I-K., Ying, H., Weber, U., Perkins,L., Tartaglia, M., Mlodzik, M., Pick, L. and Gelb, B.D. (2006) Transgenic Drosophila models of Noonan syndrome-causing RTPN11 gain-of-function mutations. Human Molecular Genetics 15: 543-553.[Pubmed Link]
Lohr, U. and Pick, L. (2005) Cofactor interaction motifs and the cooption of a homeotic Hox protein into the segmentation pathway of Drosophila melanogaster. Current Biology 15: 643-649. [Pubmed Link]
Song, J., Wu, L., Chen, Z., Kohanski, R.A. and Pick, L. (2003) Axons guided by Insulin Receptor in the Drosophila Visual System. Science 300: 502 - 505. Additional online Supplementary Material. Comment in same issue, Dickson, B.J. (2003) Science 300:440-1 [Pubmed Link]
Lohr, U., Yussa, M. and Pick, L. (2001) Drosophila fushi tarazu: a gene on the border of homeotic function. Current Biology (Cell Press), 11:1 403-1412. [Pubmed Link]
Yussa, M., Lohr, U., Su, K. and Pick, L. (2001) The nuclear receptor Ftz-F1 and homeodomain protein Ftz interact through evolutionarily conserved protein domains. Mechanisms of Development 107: 39-52. [Pubmed Link]
Publications from 1990-2000:
Pick, L., Lohr, U. and Yu, Y. (2000) A Double Interaction Screen to isolate DNA binding and protein tethered transcription factors. In "Yeast Hybrid Techniques - genetic assay system for protein interactions." Ed. L. Zhu and G.J. Hannon. Eaton Publishing, Natick, MA.Zhao, J. J., Vanario-Alonso, C.E. and Pick, L. (1999) Targeted ribozymes to study gene function in Drosophila. In "Intracellular Ribozyme Applications: Principles and Protocols" Ed. J. J. Rossi and L. Couture. Horizon Scientific Press, Norfolk, England.Yu, Y., Yussa, M., Song, J., Hirsch, J. and Pick, L. (1999) A Double Interaction Screen identifies positive and negative ftz gene regulators and Ftz-interacting protein. Mechanisms of Development 83: 95-105. [Pubmed Link]
Pick, L. and Lawrence, P.A. (1998) How does the fushi tarazu gene activate engrailed in the Drosophila embryo? Developmental Genetics 23:28-34. [Pubmed Link]
Pick, L. (1998) Segmentation: painting stripes from flies to vertebrates. Developmental Genetics 23:1-10. [Pubmed Link]
Han, W., Yu, Y., Kohanski, R.A. and Pick, L. (1998) An essential site in the ftz proximal enhancer interacts with multiple transcriptional activators. Molecular & Cellular Biology18: 3384-3394.Yu, Y., Li, W., Su, K., Yussa, M., Han, W., Perrimon, N. and Pick, L. (1997) The nuclear hormone receptor Ftz-F1 is a cofactor for the Drosophila homeodomain protein Fushi Tarazu. Nature 358: 552-555. [Pubmed Link]
Zhao, J.J., Lazzarini, R.A. and Pick, L. (1996) Functional dissection of the mouse HoxA5 gene. EMBO Journal 15: 1313-1322. [Pubmed Link]
Vanario-Alonso, C.E., O’Hara, E., McGinnis, W. and Pick, L. (1995) Targeted ribozymes reveal a conserved function of the Drosophila paired gene in sensory organ development. Mechanisms of Development 53: 323-328. [Pubmed Link]
Jost, W., Yu, Y., Pick, L., Preiss, A. and Maier, D. (1995) Structure and regulation of the fushi tarazu gene from Drosophila hydei. Roux’s Archives of Developmental Biology 205: 160-170.Gutjahr, T. Alonso, C. Pick, L. and Noll, M. (1994) Multiple regulatory elements direct the complex expression pattern of the Drosophila segmentation gene paired. Mechanisms of Development 48: 119-128. [Pubmed Link]
Yu, Y. and Pick, L. (1995) Non-periodic cues generate seven ftz stripes in the Drosophila embryo. Mechanisms of Development 50: 163-175. [Pubmed Link]
Zhao, J., Lazzarini, R.A. and Pick, L. (1993) The mouse Hox 1.3 gene is functionally equivalent to the Drosophila Sex combs reduced gene. Genes & Development 7: 343-354. [Pubmed Link]
Zhao, J. and Pick, L. (1993) Generating loss-of-function phenotypes of the fushi tarazu gene with a targeted ribozyme in Drosophila. Nature 365:448-451. [Pubmed Link]
Han, W., Yu, Y., Altan, N. and Pick, L. (1993) Multiple proteins interact with the fushi tarazu proximal enhancer. Molecular & Cellular Biology 13: 5549-5559. [Pubmed Link]